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United States
Mehlville
Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg
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Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg, Mehlville

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Check rooms and rates
From169US$ /night
Check-in
23Mar2026Select date
Check-out
24Mar2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4250 Midamerica Lane, Mehlville, Missouri, United States
Perfect
9.2
9.4
/10
4.4
4.4
/5
“The hotel's location is perfect for accessing all the highlights of Saint Louis, making our stay truly lovely!”view full review

Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg is a 3-star accommodation known for its modern design and comfort. Guests have access to a heated indoor pool, a fitness center, and complimentary Express Start Breakfast. Located in Mehlville, this hotel offers convenient amenities for both leisure and business travelers.

Rooms & Amenities

Rooms at Holiday Inn Express feature modern conveniences including a 49-inch flat-screen TV, microwave, mini-fridge, and Keurig coffee maker. Each guest room is equipped with bedside outlets, high-speed internet, and various bedding options designed for comfort. Suites are available, accommodating up to four guests with additional space.

Dining & Nearby Options

The hotel offers a complimentary breakfast that includes a variety of hot and fresh items, served daily in the Great Room. For lunch and dinner, Frailey's Southtown Grill is a nearby dining option located within a shopping center, specializing in chicken wings and offering a full menu.

Leisure & Recreation

Leisure facilities include a heated indoor pool and a well-equipped fitness center featuring treadmills, elliptical machines, and free weights. Guests are welcome to relax outside on the new Guest Patio that features a fire pit, providing a cozy spot to unwind after a day of activities.

Business & Local Area

Holiday Inn Express provides two meeting rooms suitable for small business functions or social gatherings. The hotel offers complimentary parking and is conveniently located near public transport options such as South County Center bus station. Guests can easily explore nearby attractions like the Gateway Arch and the St. Louis Zoo.

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Select your room type

Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Standard Room Two Queen Beds
Standard Room Two Queen Beds
2 persons
305 sq. feet 
2 King Size Beds
Heating
Air conditioning
room details
Deluxe King Room
Deluxe King Room
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Heating
Air conditioning
room details
Suite
Suite
2 persons
305 sq. feet 
2 King Size Beds
Heating
Air conditioning
room details
Standard Double Suite
Standard Double Suite
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Heating
Air conditioning
room details
Click button to see more rooms
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Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg offers amenities for your comfortable stay and unforgettable experiences
Delicious Breakfast!
“The breakfast selection was excellent, with every dish being hot and freshly prepared. It truly set a wonderful tone for our day.” view full review
Immaculate Room!
“Our room was impeccably clean and incredibly comfortable, making it a perfect retreat after a long day.” view full review
Extra Touches!
“The added touch of milk and fresh cookies in the evenings was good, making our stay feel even more special.” view full review
Impressive Cleanliness!
“The hotel maintained an really good level of cleanliness throughout all areas, comparable to a hospital's standards. It left us feeling comfortable and safe.” view full review
Facilities: Perfect
9.2/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's buffet
  • Toys

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers

Room features

  • Air conditioning
  • Heating
  • Garden furniture

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg Location

4250 Midamerica Lane, Mehlville, Missouri, United States
Map view
4250 Midamerica Lane, Mehlville, Missouri, United States
City landmarks
Landmark
Mattiese Shopping Center
4500 ft
Landmark
Butler Hill Church
2400 ft
Church
Crosspoint Church
3000 ft
Landmark
Saint Louis College of Health
3200 ft
Landmark
Missouri Civil War Museum
4.0 mi
Landmark
Assembly of God South Side Church
4200 ft
Landmark
Keller Plaza 8
1.2 mi
Church
Apostolic Faith Church
1.0 mi
Church
The Church of Jesus Christ of Latter-day Saints
1.2 mi
Landmark
Tee Time Family Fun Ctr
1.2 mi
Landmark
Forever Living Church of God
1.2 mi
Landmark
Fountain Temple Church of God in Christ
1.2 mi
Landmark
First Unity Church of Saint Louis
1.2 mi
Church
Saint Margaret Mary Alacoque Church
1.3 mi
Landmark
South Country Church
1.3 mi
Church
Prince of Peace United Church of Christ
1.4 mi
Church
Canan Baptist Church
1.4 mi
Church
Mary Mother of the Church
1.5 mi
Landmark
BounceU of St. Louis
1.7 mi
Landmark
Mary Mother of the Church Parish Hall
1.6 mi
Church
Gospel Assembly
1.6 mi
Church
Assumption Catholic Church
1.6 mi
Landmark
Gospel Assembly Church
1.6 mi
Landmark
South County Christian Center
1.6 mi
Church
South County Baptist Church
1.7 mi
Landmark
Nazareth Convent
1.8 mi
Church
Nazareth Living Center Chapel
1.8 mi
Park
Kennedy Recreation Complex
1.9 mi
Landmark
Kingdom Hall
1.9 mi
Park
Suson Park
2.2 mi
Nearby
Assembly of God South Side Church
600 ft
Saint Louis College of Health
1900 ft
Restaurants
Taco Bell
1700 ft
4320 Butler Hill Road
Burger King
1600 ft
4324 Butler Hill Rd
Soulard Gyro
2100 ft
4337 Butler Hill Rd
Panda
1900 ft
4337 Butler Hill Rd Ste E
Getting around
City Centre
Mehlville3 min  ·  700 ft
Airports
St. Louis Lambert International Airport (STL)56 min  ·  23.0 mi
Belleville, IL (BLV)95 min  ·  39.1 mi
Train
Shrewsbury Metrolink Station19 min  ·  7.7 mi
Sunnen Metrolink Station21 min  ·  8.6 mi
Bus
Bus stop5 min  ·  1400 ft
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg provides visitors with a free full breakfast. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
104
Former name
holiday inn express & suites - st. louis south - i-55, an ihg hotel

Reviews and Ratings

Feedback about Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg from previous guests about their experience.
Review score
Based on 162 verified reviews
9.4/10
Perfect
96%
Recommend
Cleanliness
9.3/10
Comfort
9.4/10
Facilities
9.2/10
Free Wi-Fi
9.5/10
Location
9.3/10
Paid Wi-Fi
7.4/10
Staff
9.3/10
Value for money
8.7/10
Guest reviews
based on 110 reviews
9.2/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews

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Check-in
23Mar2026Select date
Check-out
24Mar2026Select date
Rooms and Guests2 Guests, 1 Room
  • Overview
  • Rooms
  • Price calendar
  • Facilities
  • Location
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